Kybella is an FDA-approved nonsurgical injectable for reducing fat under the chin (submental area). It dissolves fat cells that cause a double chin, helping define the jawline. The treatment is minimally invasive, usually requires no downtime, but may cause mild to moderate side effects, with swelling being the most common.
Kristina Cadwell
April 3, 2024
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5 min read
Here, you’ll find everything you need to know about Kybella swelling: what causes it, how long it lasts, and what you can do to prevent or reduce it.
What Causes Kybella Swelling?
Kybella swelling results from the body’s inflammatory reaction to the treatment. Swelling is especially common in people who have a lower tolerance to Kybella’s main ingredient, deoxycholic acid.
The following may additionally increase the chances of Kybella swelling:
Large fat deposits under the chin that require greater doses of Kybella
Many injection sites close together
First-time treatment
Inexperienced Kybella injectors
It is crucial to book a Kybella treatment at a reputable clinic with experienced, Kybella-certified medical providers.
How Long Does Kybella Swelling Last?
Inflammation and swelling usually appear right after the treatment. Patients report that the swelling often peaks two to three days after the treatment and resolves within one month.
The recommended time between Kybella treatments is one month. Consult your medical provider before scheduling another treatment if swelling from your first treatment has not resolved by then.
Luckily, there are things you can do to minimize the chances of swelling after the Kybella treatment.
Limit Salt and Sugar
High-sodium foods can cause water retention and bloating, and sugary foods cause inflammation. Since injectables carry the risk of an inflammatory reaction, it is best to avoid foods that additionally increase inflammation and swelling. Avoid salt and sugar intake a few days before and after the treatment.
Refrain from Alcohol and Nicotine
Alcohol widens blood vessels, increasing the chance of swelling, and nicotine also has pro-inflammatory properties. Like salt and sugar, it is best to avoid them a few days before and after the treatment to minimize complications and promote optimal healing.
Avoid Blood-Thinning Medications
Some medical professionals advise patients to discontinue the use of blood thinners, such as aspirin and ibuprofen, one week before the procedure. These may increase the chance of excessive bleeding during the treatment and cause swelling.
Take Antihistamines
OTC medications that help relieve allergies, such as Benadryl and Zyrtec, can also reduce swelling after Kybella. Some doctors recommend taking one pill the day before and one pill the day after the treatment. Take antihistamines only according to your doctor’s instructions.
Don’t Use Fatty Acids Supplements
Fatty acid supplements like fish, cod, krill, and flax oil have mild blood-thinning properties. Medical providers sometimes advise avoiding them for several days before the Kybella treatment.
Be Careful with Skin Products and Treatments
Patients shouldn’t use products that contain glycolic acid, alpha-hydroxy acid, retinol, and retinoids a few days before and after the treatment. These ingredients may cause irritations and increase the risk of swelling.
Doctors recommend refraining from intense workouts, such as jogging, swimming, HIIT, cardio exercises, and heavy lifting for 24 hours after Kybella. Strenuous exercise raises blood flow to the treated area, increasing the chance of swelling.
Avoid Exposure to Sun and Heat
Sun and heat dilate blood vessels and increase blood flow, exacerbating swelling after Kybella. Avoid exposure to sun, tanning beds, hot tubs, and saunas for 3-5 days following the treatment.
How to Treat Kybella Swelling
If swelling appears after Kybella despite your best efforts to avoid it, the following aftercare tips will help you reduce it.
Take a Pain Reliever
If you experience swelling and discomfort, you may take an over-the-counter pain-relieving medication, such as Tylenol.
Apply Cold Packs
The cold helps constrict blood vessels and slow down blood flow, relieving inflammation and swelling. Hold ice wrapped in a towel or a bag of frozen produce on the treated area for 15 minutes. Repeat this several times the first day after the treatment.
Compress the Treated Area
Wrap a chinstrap around the chin and neck for more compression. The pressure helps keep the blood and fluids from pooling in the treated tissue. Use it the first few days following the treatment to soothe pain and decrease swelling.
Elevate Your Head During Sleep
Patients are advised to sleep with their heads in an upright position during the first 2-3 days after Kybella. Like compression, this helps keep the blood from pooling. Use two or three pillows to elevate the head.
Drink Plenty of Water
Kybella injectables destroy fat cells, and the lymphatic system removes them from the body. To support the smooth functioning of the lymphatic system, drink at least eight glasses of water daily.
Note: For more tips, make sure to read our guide to Kybella aftecare.
When Should You See a Doctor for Kybella Swelling?
If the swelling doesn’t subside after one month, or if you have concerns about its severity and duration, visit your medical provider.
If the swelling is accompanied by other symptoms, it may be a sign of an infection or another serious side effect. They are extremely rare, but should you experience any of the following symptoms, see your doctor immediately:
An uneven smile
Weakness in facial muscles
Difficulty swallowing
Open sores and ulcers
Oozing from open sores
Hair loss at the injection site
Damaged skin tissue (necrosis)
Conclusion
Kybella is the only FDA-approved fat-reduction injectable treatment for the submental area. Mild-to-moderate swelling is a common Kybella side effect, and it usually resolves on its own quickly. With proper care before and after the procedure, you’ll need minimal recovery and will soon enjoy a visibly improved jawline and neck profile.
PA Kristina Cadwell graduated from Arizona State University with a Bachelor of Science degree in Biology. She then completed the Physician Assistant program at A.T. Still University graduating with a Masters of Medical Science degree. Kristina has been working in the Aesthetic Medical field for over 15 years. She is certified in neurotoxin cosmetic injection, dermal fillers, laser therapy, chemical peels, and ultrasound. She is known for producing natural results and has extensive knowledge in nutrition, hormone balancing, microbiome health, diet and exercise. Her latest endeavor is the Vibrant Skincare Line, a microbiome-friendly line of skincare that works with your body. Her passion and the reason she does everything she does? Helping you achieve vibrant skin from the inside out.