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Natural Skincare Products: 27 Products Worth Checking Out

Kristina Cadwell  
June 29, 2023  

Product labels can be confusing because some information is mandatory and strictly regulated, while other is open to interpretation. For example, using the word “natural” on skincare product labels isn’t regulated, so consumers need to check if the product is really made from clean, naturally sourced ingredients.

One of the ways to ensure you are getting premium-quality, natural skincare products is to pay attention to recommendations from medical cosmetic professionals. They often endorse brands that use medical-grade, non-toxic ingredients, and it is worth trying them out.

This article lists 27 skincare products from reputable brands such as Osmosis MD, SkinMedica, Alastin, and iS Clinical. Learn how they can help clear your skin and restore a youthful glow to your complexion.

Natural skincare products

27 Best Natural Skincare Products

Skin experts use the term “natural” or “holistic” in skin care to refer to products with plant-based ingredients free of parabens, sulfates, artificial fragrances, dyes, harmful additives, and toxins. Natural skincare products are less likely to cause irritation or adverse effects, and they gently nourish, hydrate, and protect the skin from environmental damage.

Note: Learn more about holistic skin care.

The following products are made primarily from clean, botanically sourced ingredients, providing various health benefits for the skin.

1. Osmosis MD Deep Clean Detox Cleanser

Deep Clean Detox Cleanser by Osmosis MD

Deep Clean Detox Cleanser by Osmosis MD is a gentle cleanser for all skin types, with citrus oils (orange, lemon, grapefruit) and coconut. It is especially helpful for acne-prone skin because it thoroughly cleanses the pores of all impurities and excess sebum.

Apply one pump on damp skin and massage gently, then rinse. Use it once or twice daily.*

2. skinbetter Oxygen Infusion Wash

Oxygen Infusion Wash by skinbetter

Like all skinbetter products, Oxygen Infusion Wash is free of parabens, sulfates, fragrances, and dyes. It features slow-releasing alpha-hydroxy acids (AHAs) to gently remove impurities and an infusion of oxygen to refresh and energize the complexion. It is best suited for normal to oily skin.

Apply on damp skin and gently massage, then rinse with warm water. Use it in the morning and evening.*

3. Alastin Gentle Cleanser

Gentle Cleanser by Alastin

Gentle Cleanser by Alastin is designed to thoroughly cleanse without drying and irritating the skin. Oat kernel extract, bisabolol, and oat beta-glucan have calming properties, while D-panthenol softens and moisturizes the skin. It is suitable for all skin types.

Apply one pump on damp skin, massage gently, and rinse. Use it once or twice daily.*

4. SkinMedica AHA/BHA Exfoliating Cleanser

AHA/BHA Exfoliating Cleanser by SkinMedica

AHA/BHA Exfoliating Cleanser by SkinMedica gently removes dead skin cells, excess oil, and other skin impurities. Combining AHAs (lactic, glycolic, citric, and malic acids) and BHA (salicylic acid) helps to exfoliate the top skin layer, revealing more even, softer skin. The product is suitable for all skin types.

Apply a small amount on damp skin, gently massage, and rinse. If used in the morning, follow with sunscreen because AHAs increase the skin’s sensitivity to the sun.*

Note: If you're not sure which sunscreen to use, check out our tips on how to choose a sunscreen that works for your skin type.

5. Osmosis MD Quench Moisturizer

Quench by Osmosis MD

Quench by Osmosis MD is a lightweight formula providing deep hydration thanks to emollients (moisture-retaining ingredients), such as shea butter, jojoba oil, and squalene. It helps to restore the skin’s resilience and glow.

Use it twice daily after cleansing, toning, and applying a serum. Use a small amount.*

6. SkinMedica TNS Recovery Complex

SkinMedica TNS Recovery Complex

TNS Recovery Complex by SkinMedica is a powerful anti-aging solution incorporating the brand’s proprietary TNS blend – naturally secreted growth factors that effectively reduce wrinkles and improve pigmentation issues.

Gently apply one pump on the face (and neck, optionally) in the morning and evening.*

Note: If you're struggling with prominent hyperpigmentation, check out the best ways to get rid of dark spots on the face.

7. SkinMedica Vitamin C+E Complex

Vitamin C+E Complex by SkinMedica

Vitamin C+E Complex by SkinMedica is a powerful antioxidant formula featuring stabilized and natural forms of vitamins C and E. They are often the star ingredients in anti-aging skin care because they help repair and protect the skin from environmental damage. The product is suitable for all skin types.

Gently apply one pump in the morning and evening. Use after cleansing and toning and before moisturizing.*

8. iS Clinical Brightening Complex

Brightening Complex by iS Clinical

Brightening Complex by iS Clinical contains a proprietary blend of brightening and hydrating botanicals, including Norwegian kelp extract, arbutin and mushroom extract, Imperata cylindrica root extract, vitamin C, glycerin, and squalene. They calm and soothe the skin, helping to improve skin tone and reduce pigmentation irregularities.

Apply a small amount to the skin after cleansing. Use in the morning and evening.*

9. iS Clinical Copper Firming Mist

Copper Firming Mist by iS Clinical

Copper Firming Mist by iS Clinical is a refreshing spray that provides instant hydration and support for healthy skin. Copper promotes collagen synthesis, tightening the skin and improving elasticity, while botanical antioxidants and resveratrol provide all-day antioxidant protection from external factors.

Lightly spray on clean skin in the morning and evening or throughout the day to refresh tired skin.*

10. iS Clinical Hydracool Serum

Hydra-cool Serum by iS Clinical

Hydracool Serum by iS Clinical is a high-concentration blend of potent rejuvenating ingredients, including hyaluronic acid, Centella asiatica, vitamin B3, and mushroom extract. Together they act on premature aging skin, helping to reduce wrinkles, improve skin tone, and provide intense hydration. It is suitable for all skin types.

Gently apply and smooth over the face and neck twice daily.*

11. iS Clinical Youth Eye Complex

Youth Eye Complex by iS Clinical

Youth Eye Complex by iS Clinical is a dream cream for people with visible aging signs around the eyes. It uses natural ingredients, such as hyaluronic acid, copper tripeptide growth factor, Centella asiatica extract, and Pseudoalteromonas ferment extract to reduce dark circles, puffiness, and fine lines and regenerate the area.

Lightly dab ½ pump around the eyes, avoiding inner eye corners. Use in the morning and evening.*

Note: Check out these 18 best eye creams for dark circles.

12. Osmosis MD Nourish Avocado Facial Oil

Avocado Facial Oil by Osmosis MD

Natural facial oils are made from pure, cold-pressed plant oils to provide intense hydration to the skin. Nourish Avocado Facial Oil by Osmosis MD is certified organic and uses a simple, highly concentrated formula containing oils such as avocado, jojoba, sunflower, lavender, sea buckthorn, and more.

The rich fatty acid content in the product is beneficial for dry skin, and avocado’s anti-inflammatory properties can help people with acne, eczema, and psoriasis.

Shake the bottle and apply a few drops on the face and neck. Massage gently.*

Note: Learn more about the benefits of avocado oil for the skin and how it can help with dark spots, wrinkles, UV damage, and more.

13. Elta MD UV Pure Broad-Spectrum SPF 47

UV Pure by Elta MD

UV Pure by Elta MD is a gentle, chemical-free sunscreen for adults and children. It absorbs quickly and provides strong protection against UVA and UVB radiation thank to natural mineral sunscreen agents, zinc oxide and titanium dioxide. Another active ingredient in the product, vitamin C, helps to strengthen the skin’s protective barrier and reduce aging signs. The product may leave a white residue.

Apply 15 minutes before sun exposure and reapply every two hours (or 80 minutes after swimming).*

14. Alastin SilkSHIELD All Mineral Sunscreen SPF 30

SilkSHIELD Mineral Sunscreen by Alastin

SilkSHIELD All Mineral Sunscreen by Alastin is infused with potent ingredients to protect the skin from sun exposure and improve visible signs of aging. It uses the company’s innovative TriHex technology, which promotes collagen and elastin synthesis to reduce aging signs and improve skin health. Zinc oxide provides natural protection from UV radiation, while ectoin helps repair existing sun damage.

Apply liberally 15 minutes before sun exposure and reapply every two hours or 40 minutes after swimming.*

15. Vibrant Skin Hydracell Gold Mask

Hydracell + Gold Mask by Vibrant Skin

Hydracell Gold Mask by Vibrant Skin is a medical-grade, detoxifying facial mask featuring charcoal, which effectively removes skin impurities, and 24K gold, which improves skin elasticity. The mask helps reduce aging signs and restore the skin’s youthful glow.

Apply on cleansed and dry skin. Leave on for 15-20 minutes and rinse or massage the remaining product into the skin.*

16. Vibrant Skin Cinnamon Coffee Scrub

Cellulite Detox Sugar Scrub by Vibrant Skin

Recipes for cellulite-ridden skin abound, but not many work. Cinnamon Coffee Scrub by Vibrant Skin softens the skin and reduces the appearance of cellulite with regular use. Infused with natural ingredients such as coffee, cinnamon, vanilla, avocado oil, and aloe, it promotes relaxation while improving circulation and helping to remove toxins and excess water. The overall effect of the treatment includes minimized cellulite appearance, softer skin, and improved hydration.

Apply the paste on areas affected by cellulite. Massage in circular motions for two minutes. Rinse with lukewarm water. Use it every time you shower.*

Note: Learn what causes cellulite and how to reduce its appearance.

The following recommendations are dietary supplements that help improve the skin from within.

17. Osmosis MD Ageless Vitality Elixir

Ageless Vitality Elixir - Osmosis MD

Ageless Vitality Elixir contains Osmosis MD’s proprietary liquid fulvic formulation – a blend of naturally occurring humic acids, fulvic acids, plant-sourced minerals, vitamins, amino acids, and phytochemicals. It also contains 24K edible gold. These nutrients act on HGH and IGF-1, the hormones affecting growth and aging, and contribute to systemic rejuvenation. They also improve digestion and neutralize environmental pollutants, helping to clear the skin.

Shake before use. Spray 5 pumps in the mouth in the morning and evening or 7 pumps if you weigh over 175 lbs.*

18. Osmosis MD Digestive Support Supplement

Digestive Support by Osmosis MD

Digestive Support Supplement clears the skin by improving digestion. Formulated with a blend of enzymes including protease, bromelain, papain, peptidase, and pancreatin 10X, it helps break down essential nutrients, enhances their absorption, and reduces toxins to support a healthy gut and radiant skin.

Start with one capsule 1-3 times daily before meals. If needed, increase to two capsules 1-3 times daily.*

19. Osmosis MD Immune Activator

Immune Activator by Osmosis MD

Immune Activator is formulated with the company’s proprietary blend of ingredients, including ozonized ethyl oleate (sweet wormwood extract), which neutralizes toxins, reduces inflammation, and helps repair wounds. This supplement improves the skin by defending against oxidative stress and improving overall immunity.

Place a full dropper under the tongue for 7 minutes and then swallow or discard. The product can also be used topically on problematic skin.*

20. Osmosis MD Recovery Prebiotic Omega & Fat Pad Renewal Elixir

Recovery Prebiotic Omega + Fat Pad Renewal Elixir by Osmosis MD

Recovery Prebiotic Omega & Fat Pad Renewal Elixir is a natural alternative to fillers because it addresses volume loss by restoring essential nutrients, such as probiotics and omega-7 acids. It is formulated with a proprietary blend of sea buckhorn and macadamia oil, which provide antioxidant support and reduce inflammation. By improving microbiome balance, the elixir helps volumize the skin, improve aging signs, and reduce rosacea symptoms.

Shake before use and take 1 tbsp once daily for probiotic and omega fats replenishment or 1 tbsp twice daily for fat volume loss.*

21. Osmosis MD Regenerate Supplements

Regenerate - Liver and Collagen Renewal supplements by Osmosis MD

Regenerate contains a blend of collagen and other essential amino acids, vitamins, and antioxidants (Glutathione and SOD) that help detox the liver and protect and repair the skin. Skin experts recommend it for dark (liver) spots, melasma, aging skin, and hair loss.

Start with 6 capsules daily for 4+ months, with or without food. After achieving the desired results, maintain them using 3 capsules daily.*

22. Osmosis MD Skin Clarifier

Skin Clarifier by Osmosis MD

Skin Clarifier is a 10-day cleansing treatment that helps remove toxins and mucus from the digestive tract, lungs, and sinuses to reduce acne, eczema, dryness, and other skin issues. It is formulated with a patented blend of mucus-cleansing ingredients, including mullein leaf powder, plantain leaf powder, lobelia herb powder, and lactase.

Take 8 capsules 2 times daily on an empty stomach. Avoid dairy and fried foods during the 10-day cleansing treatment.*

23. Osmosis MD Skin Defense

Skin Defense by Osmosis MD

Skin Defense is a powerful formula with a patented blend of natural detoxifying ingredients, including N-acetyl cysteine, activated carbon/charcoal, glutathione, and L-ornithine.  It rids the body of heavy metals, pesticides, plastics, food preservatives, and other toxins. The treatment helps balance hormones and improve immune function, promoting clear, blemish-free, radiant skin.

Take 2-3 capsules daily at least 1 hour before or after medications.*

24. Osmosis MD Skin Perfection Elixir

Skin Perfection Elixir - Osmosis

Formulated with Osmosis MD’s trademark liquid fulvic solution (containing 70+ critical minerals) and 24K edible gold, Skin Perfection Elixir effectively neutralizes skin toxins and improves digestion. It helps reduce skin imperfections related to poor gut health, such as acne, rosacea, eczema, and psoriasis.  

Shake before use. Spray 5 pumps in the mouth in the morning and evening or 7 pumps if you weigh over 175 lbs.*

25. Osmosis MD Sun Defense Bronzing Elixir

Sun Defense Bronzing Elixir by Osmosis

Sun Defense Bronzing Elixir is a great solution for guilt-free tanning because it reduces the damaging effects of UV radiation while encouraging the body’s natural tanning process. It is formulated with the company’s proprietary fulvic and humic mineral blend and 24K edible gold to stimulate new cell growth and healthy skin.

Shake before use. Take 5 pumps 1 hour before sun exposure or 7 pumps if you weigh over 175 lbs. Retake after 3 hours. Use alone or as a support to topical sunscreen.*

26. Vibrant Collagen

Collagen supplements by Vibrant Skin

Collagen is the most abundant skin-building protein responsible for skin firmness and strength. It degrades with age, and Vibrant Collagen can help enhance its production to pause and reverse aging signs. The supplement is formulated with a unique blend of three collagen peptides shown to increase bone strength and improve skin elasticity.

Mix 13 grams (approximately one scoop) in 8 ounces of water and drink daily or as your healthcare provider recommends.*

27. Vibrant Skin Brilliance

Skin Brilliance by Vibrant Skin

Skin Brilliance by Vibrant Skin is a natural supplement with glutathione as its star ingredient. Glutathione is a potent antioxidant, protecting the cells from oxidative stress and DNA damage. It also supports detoxification, clearing the skin and providing a brighter, more radiant complexion.

Take approximately 2 pumps and hold in your mouth for 30 seconds, then swallow or discard (as recommended by your healthcare provider).*

Note: Read our blog post on how to take glutathione effectively.

*DISCLAIMER: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Natural topical products and supplements are a popular alternative to conventional skin care. They often address the root causes of problematic skin, helping to repair skin issues from within while improving overall health.

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About the Author:
Kristina Cadwell
PA Kristina Cadwell graduated from Arizona State University with a Bachelor of Science degree in Biology. She then completed the Physician Assistant program at A.T. Still University graduating with a Masters of Medical Science degree. Kristina has been working in the Aesthetic Medical field for over 10 years. She is certified in neurotoxin cosmetic injection, dermal fillers, Plasma Pen skin tightening, chemical peels, and laser therapy. She is known for producing natural results and has extensive knowledge in diet and exercise allowing her to help you achieve vibrant skin from the inside out.
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