Jeuveau vs. Botox: What’s the Difference?

According to a global survey by the International Society of Aesthetic Plastic Surgery, botulinum toxin is the most popular non-surgical treatment for men and women across all age groups. Most patients know botulinum toxin by the brand name Botox, though it is only one of the five FDA-approved neurotoxin injections. The other four include Dysport, Xeomin, Jeuveau, and the most recently approved - Daxxify.

This article maps the differences and similarities between Jeuveau and Botox, helping patients understand what to expect from the treatment.

Jeuveau vs. Botox: Overview

Jeuveau and Botox are injectable treatments popularly used in the cosmetics industry to reduce fine lines and wrinkles.

The following table summarizes the two neurotoxins’ differences and similarities.

Jeuveau vs. Botox: Similarities and Differences

Jeuveau and Botox are made from the same substance, but are differently formulated, and each neuromodulator is approved for different uses.

FDA Approval

Botox was initially approved in 1989 for therapeutic use, and in 2002 for cosmetic use.

The FDA approved Jeuveau for cosmetic use in 2019. It is also called “NewTox” because it’s one of the most recent additions to the family of neuromodulators.

Formulation

Jeuveau and Botox are made from botulinum toxin type A, a neurotoxin derived from the Clostridium botulinum bacterium.  

Botox is formulated with onabotulinumtoxinA, a distinct subtype of botulinum toxin type A that contains a unique amino acid sequence. The formula also includes complexing proteins that coat and protect the active neurotoxin.

Jeuveau is formulated with prabotulinumtoxinA, another subtype of botulinum toxin type A. It also contains complexing proteins but uses a different manufacturing and purification technology, potentially causing a quicker onset of results.  

Note: Learn how Botox differs from Xeomin, the purified form of botulinum toxin type A.

Use Cases

The advantage of Botox over Jeuveau is its multitude of applications. Cosmetic Botox is FDA-approved to treat glabellar (frown) lines, crow’s feet, and forehead wrinkles. Botox has a long history of medical uses as well, effectively treating excessive underarm sweating, drooling, eyelid spasms, bladder issues, and migraines.

Jeuveau is only used for cosmetic purposes. It is indicated for glabellar lines, with more treatment areas pending approval.

Medical professionals often use neuromodulators in off-label procedures to reduce wrinkles in areas that are not FDA approved. This use is safe when performed by licensed and experienced providers.

Note: Learn about the most common FDA-approved and off-label Botox areas.

Procedure Duration and Frequency

The procedure of administering Jeuveau and Botox is similar. It takes 15-30 minutes and includes cleansing the patient’s skin, applying numbing cream on the target area, and injecting the neurotoxin.

Medical providers recommend waiting at least three months before the next session. One of the reasons for this is to avoid developing botulinum toxin resistance. Patients usually schedule their treatments every three to six months to continue the wrinkle-smoothing effects.

Results

The results of both treatments are smoother or entirely eliminated wrinkles in the treatment area.

The skin after a Jeuveau treatment is visibly improved within 1-3 days, and it takes 7-10 days to experience the full results. They last 3-4 months.

Botox patients usually see the first results within 3-5 days, and full results appear within 10-14 days. They typically last 3-4 months.

Side effects

Jeuveau and Botox are FDA-approved and safe when performed by skilled medical professionals. However, many patients experience mild side effects at the injection site. These include:

• Bruising
• Swelling
• Redness
• Pain

Rare and more severe side effects can occur when the toxin spreads to adjacent areas. These side effects include:

• Allergic reactions
• Swallowing difficulties
• Breathing difficulties
• Headaches
• Drooping eyelids
• Bladder control issues
• Muscle weakness

Note: Learn more about potential Botox side effects and how to mitigate them.

Cost

The cost of a Jeuveau or Botox treatment varies depending on the treatment area, the severity of wrinkles, the medical provider’s expertise, and the location of their practice.

The average Jeuveau injectable price per unit is $8 - $20, and patients usually require 20 units per treatment.

At Vibrant Skin Bar, one Botox unit costs $12.50, and patients typically need 20 units per treatment area.

Jeuveau vs. Botox: How to Choose?

Jeuveau and Botox are FDA-approved and well-tolerated by most healthy adults. They are equally effective in providing quick, skin-smoothing results.

One advantage of Botox over Jeuveau is that the practice is accompanied by 30+ years of comprehensive clinical evidence on safety and efficacy, while the data for Jeuveau is limited.

Consult a board-certified medical provider to determine whether Jeuveau or Botox is more suitable for you and the amount of neurotoxin needed for desired results.

Note: If you're not sure about Botox or Jeuveau, discover other Botox alternatives.

Conclusion

Neurotoxin injectables are among the most popular non-surgical treatments, judging by the millions of people who undergo the procedure each year. Botox is the most comprehensive and well-known wrinkle eraser, but similar, alternative treatments exist – such as the innovative Jeuveau.

Jeuveau and Botox provide similar wrinkle-reducing results and show a high safety profile. Discuss your options with a trusted medical provider to ensure you reach your desired beauty goals.

For safe and impressive results, book your next Botox session in Phoenix!