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Radiesse vs. Juvéderm: What’s the Difference?

Kristina Cadwell  
May 15, 2023  

Dermal fillers are a non-invasive cosmetic treatment that helps minimize the effects of aging by replenishing lost volume in the skin. The treatment is gaining popularity because it provides excellent, natural-looking results. Satisfied patients report a dramatic reduction of lines and wrinkles, and restored facial contours.

Radiesse and Juvéderm are two of the most popular dermal filler brands. This article will help you understand their differences and which brand may be more suitable for your skin concerns.

Radiesse vs. Juvederm: The differences between the two dermal fillers

What Is Radiesse?

Radiesse is an FDA-approved gel injection based on calcium hydroxylapatite, a mineral typically found in bones and teeth. The filler restores lost volume and provides an immediate plumping of hollow facial areas.

Unlike other filler types, due to its composition, Radiesse stimulates the gradual production of collagen. This means that full results of the treatment are visible after several weeks. These delayed effects distinguish Radiesse from other dermal fillers.  


Note: Read our article if you want to learn about the benefits of collagen for the skin.


What Is Juvéderm?

Juvéderm is an FDA-approved gel injection based on hyaluronic acid (HA), a carbohydrate found in our tissues. It helps attract and retain moisture in treated areas, plumping up and rejuvenating the skin. The results are immediate and last until the body dissolves the injected HA, which is typically after one year.


Note: Find out what are the best products for skin rejuvenation.


The brand has several products with different HA concentrations and formulas designed to target different facial areas and concerns. The advantage of HA-based dermal fillers like Juvéderm is that they can be dissolved with the enzyme Hyaluronidase if the patient isn’t satisfied with the results.

Radiesse Vs. Juvéderm: What Are the Differences?

Radiesse and Juvéderm provide similar benefits, but they also differ in several ways.  

JuvédermRadiesse
Main ingredientHyaluronic acidCalcium hydroxylapatite
Treatment areasMarionette lines
Corners of the mouth
Sagging jowls
Wrinkled chin
Sunken cheeks
Nasolabial folds
Lips
Perioral lines
Marionette lines
Corners of the mouth
Sagging jowls
Wrinkled chin
Sunken cheeks
Nasolabial folds
Wrinkled hands
Time to first resultsImmediateImmediate volumizing and gradual rejuvenating effects
Results duration6-12 months18-24 months
Can be dissolvedYesNo

Radiesse Vs. Juvéderm Formula

The main difference between these two popular dermal fillers are the active ingredients.

Radiesse is a water-based gel mixed with calcium hydroxyapatite which boosts collagen production and plumps up the skin.

Juvéderm has a smooth consistency, based on hyaluronic acid. The brand has several products with different HA concentrations and formulas designed to target different facial areas and concerns. Some Juvéderm products are better for chin augmentation, while others plump up the lips and smooth perioral lines.

Both Radiesse and Juvéderm fillers are mixed with lidocaine to numb the treated area and minimize pain.

Radiesse Vs. Juvéderm Treatment Areas

Radiesse addresses the following skin concerns:

  • Marionette lines
  • Corners of the mouth
  • Sagging jowls
  • Wrinkled chin
  • Sunken cheeks
  • Nasolabial folds
  • Wrinkled hands

Radiesse is FDA-approved for wrinkle reduction in the back of the hands because of its collagen-boosting properties.

Juvéderm helps with the following skin concerns:

  • Marionette lines
  • Corners of the mouth
  • Sagging jowls
  • Wrinkled chin
  • Sunken cheeks
  • Nasolabial folds
  • Lips
  • Perioral lines

Juvéderm is more suitable for lip volumizing because Radiesse’s thick consistency increases the chances of forming lumps in the lips’ sensitive tissue.


Note: Learn the important things about Juvéderm lip filler and find out how long does Juvéderm last in lips.


Radiesse Vs. Juvéderm Procedure

Treatments with Radiesse and Juvéderm dermal fillers are similar.

Before the injection, the medical provider disinfects the patient’s skin in the treatment area and marks the locations where they will inject the filler. They may apply a topical numbing cream if the patient is concerned about the pain, though the injections include lidocaine.

The medical provider injects the filler into the target area. The injection process typically lasts about 15 minutes but depends on the size of the treated area. The medical provider then gently massages the area to ensure no lumps form and the filler is distributed evenly.

There is no downtime after a dermal filler procedure.

Radiesse Vs. Juvéderm Results and Duration

Dermal filler before and after images

Radiesse provides instant wrinkle reduction and skin lifting effects. In addition, the gradual collagen boost caused by the body’s reaction to calcium particles in the skin enhances the treatment results. Your skin continues to rejuvenate for months after the treatment. The effects of Radiesse may last for 18 months and even up to two years in some cases.

A Juvéderm treatment also provides immediate wrinkle reduction and skin volumizing effects. The results typically last between six and 12 months, with some Juvéderm products providing results that last up to 18 months.

Radiesse Vs. Juvéderm: Who Should Avoid the Treatments?

Most healthy adults are eligible for Radiesse and Juvéderm treatments. However, there are conditions that exclude some patients from the treatment:

  • Pregnancy and lactation
  • Severe allergies
  • Bleeding disorders
  • Skin infections and pigmentation
  • Keloids and scarring

Your chosen medical provider will examine your medical history to determine if the filler treatment is safe for you.

Radiesse Vs. Juvéderm Side Effects

Radiesse and Juvéderm cause mild side effects that resolve within a few days without the need for medical intervention.

Typical side effects include:

  • Bruising
  • Swelling
  • Redness
  • Itching

More severe side effects are rare and include:

  • Allergic reactions
  • Infection
  • Scarring
  • Blindness
  • Stroke

Radiesse Vs. Juvéderm Cost

Radiesse products may be slightly more expensive than Juvéderm, depending on the provider’s location and the patient’s skin concern. However, they also last longer. At Vibrant Skin Bar Radiesse costs $749.

Juvéderm fillers cost between $549 for Juvéderm Ultra and $850 for Voluma.

Is Radiesse Better Than Juvéderm?

Radiesse and Juvéderm differ in their active ingredients, consistency, and the skin issues they address. For that reason, your medical provider may recommend one over the other.

Radiesse may be a better choice if you want to add volume to your midface area and restore youthful facial contours. It also lasts longer.

Juvéderm is a more suitable option if you want to add volume to your lips or treat the lines above your upper lip. It is also a safer choice when it comes to potential allergic reactions, and it can be dissolved if you don’t like the results.

Both fillers offer excellent results. Your medical provider will help you pick one based on your individual needs.

Conclusion

The cosmetic industry offers many non-invasive solutions to offset premature aging skin. Dermal fillers like Radiesse and Juvéderm are among the most popular treatments because they provide instant, long-lasting results.

Talk to an experienced skin expert at Vibrant Skin Bar to help you choose between these two fillers and achieve smoother, plumper, more youthful-looking skin. And if you are interested in finding out more about juvederm comparing to other dermal fillers, make sure to read our articles Juvéderm vs. Sculptra and Juvéderm vs. Restylane.

If you want to find out how Radiesse differs from other fillers, read our article Radiesse vs. Sculptra to find out.

If you are looking for a provider of dermal fillers in Phoenix, contact our specialists at Vibrant Skin Bar.

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About the Author:
Kristina Cadwell
PA Kristina Cadwell graduated from Arizona State University with a Bachelor of Science degree in Biology. She then completed the Physician Assistant program at A.T. Still University graduating with a Masters of Medical Science degree. Kristina has been working in the Aesthetic Medical field for over 10 years. She is certified in neurotoxin cosmetic injection, dermal fillers, Plasma Pen skin tightening, chemical peels, and laser therapy. She is known for producing natural results and has extensive knowledge in diet and exercise allowing her to help you achieve vibrant skin from the inside out.
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